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KMID : 0358320070480030283
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Korean Journal of Urology
2007 Volume.48 No. 3 p.283 ~ p.290
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Predictive Factor to Regain Erectile Function after Bilateral Nerve Sparing Radical Retropubic Prostatectomy in Korean Men
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Chang In-Ho
Han Byoung-Kyu
Byun Seok-Soo
Lee Sang-Eun
Hong Sung-Kyu
Han Jun-Hyun
Yu Ji-Hyeong
Jeong Seong-Jin
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Abstract
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Purpose: To investigate the significance of various preoperative factors with regard to postoperative erectile function in Korean men undergoing a bilateral nerve sparing radical retropubic prostatectomy(BNSRRP), using the validated Korean version of the International Index of Erectile Function (IIEF-5).
Materials & Methods: Between March 2004 and March 2005, 83 consecutive patients, who underwent a BNSRRP, with preoperative IIEF-5 scores greater than 13, were retrospectively analyzed. All patients were asked to answer the IIEF-5 questionnaire during the preoperative period and 1 year postoperatively. The responses were stratified on the basis of the clinical characteristics and the preoperative predictive factors for regaining a normal erectile function(NEF: IIEF-5 score≥18) investigated.
Results: At the baseline, 56 patients(67.5%) had NEF. At the 1 year follow-up after the BNSRRP, 58(70.5%) patients reported a return of a sufficient erection for sexual intercourse, with or without oral phosphodiesterase type 5(PDE5) inhibitors, but 37(44.6%) patients regained a NEF. Of these 37 patients, 15(40.5%) were able to spontaneously regain a NEF, but 22(59.5%) needed the help of oral PDE5 inhibitors. When the patients were divided according to postoperative NEF and erectile dysfunction(ED: 14≤IIEF-5 score＜18), the preoperative IIEF-5 score was the only significant factor for predicting postoperative NEF after a BNSRRP in univariate(p=0.018) and multivariate analyses[p=0.030, odds ratio: 3.482, 95% confidence interval(CI): 1.125-10.774]. Changes in the IIEF-5 score after a BNSRRP significantly decreased for those with preoperative NEF compared with ED(-6.1±5.24 vs. -9.1±7.34, p=0.039).
Conclusion: Our data indicated that preoperative erectile function, as assessed using the IIEF-5 questionnaire, was an independent variable for predicting the recovery of erectile function after a BNSRRP when performed in Korean men.(Korean J Urol 2007;48:283-290)
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KEYWORD
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Prostate cancer, Prostatectomy, Erectile dysfunction
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